Axon guidance in the developing ocular motor system and Duane retraction syndrome depends on Semaphorin signaling via alpha2-chimaerin.
Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14669-74. doi: 10.1073/pnas.1116481109. Epub 2012 Aug 21.
Proc Natl Acad Sci U S A. 2012.
PMID: 22912401
Free PMC article.
We have recently shown that mutations in the Chimaerin-1 gene encoding the signaling protein alpha2-chimaerin (alpha2-chn) perturb axon guidance in the ocular motor system and lead to the human eye movement disorder, Duane retraction syndrome (DRS). The axon …
We have recently shown that mutations in the Chimaerin-1 gene encoding the signaling protein alpha2-chimaerin (alpha2-chn) perturb axon guid …